CanSysPlot

VCF File:

Expression File (Optional):

CADD Cutoff Value:

Number of Permutations:

Return Link:

Select TCGA Collection:

Select Mutation Type:

Select Sample ID:

Highlight Daughter Nodes of a Main GO Category

None

immune system process

detoxification

pigmentation

localization

growth

developmental process

biological process involved in interspecies interaction between organisms

multicellular organismal process

biological phase

response to stimulus

biological regulation

viral process

cellular process

reproductive process

metabolic process

rhythmic process

homeostatic process

locomotion

biological process involved in intraspecies interaction between organisms

Show Cancer Hallmark

None

Sustaining proliferative signaling

Evading growth suppressors

Resisting cell death

Replicative immortality

Sustained angiogenesis

Tissue invasion and metastasis

Genome instability

Tumor-promoting inflammation

Reprogramming energy metabolism

Evading immune destruction

Filter Edges:

Adjust p-value less than:

0.250

Layout

Standard Euler

Hide edges if the connected node is not visible

If you use the web-based application of the CanSys tool or its command-line version available on GitHub (https://github.com/JiaweiDai-create/CanSys) in your research, please cite: Common and rare germline variants, together with somatic mutations, alter the integrity of cancer hallmark regulatory networks (currently under submission).

CanSysPlot

Patient Level Gene Regulation Network Projection Using Multi Omic Data

Step 1a. Upload files for custom analysis

Step 1b. Load results from the TCGA dataset

Step 2. Draw network

Result tables

Highlight Daughter Nodes of a Main GO Category

Show Cancer Hallmark

Filter Edges:

Adjust p-value less than:

Layout

Fontsize